Maternal human telomerase reverse transcriptase variants are associated with preterm labor and preterm premature rupture of membranes.

Premature aging and short telomere lengths of fetal tissues are associated with spontaneous preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Maintenance of telomere length is performed by the enzyme telomerase. Human telomerase reverse transcriptase (hTERT) is a subunit of tel...

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Bibliographic Details
Main Authors: Caroline Marrs, Kevin Chesmore, Ramkumar Menon, Scott Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5957404?pdf=render