Virtual Screening of Acetylcholinesterase Inhibitors Using the Lipinski’s Rule of Five and ZINC Databank

Virtual Screening of Acetylcholinesterase Inhibitors Using the Lipinski’s Rule of Five and ZINC Databank

Alzheimer’s disease (AD) is a progressive and neurodegenerative pathology that can affect people over 65 years of age. It causes several complications, such as behavioral changes, language deficits, depression, and memory impairments. One of the methods used to treat AD is the increase of acetylchol...

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Bibliographic Details
Main Authors: Pablo Andrei Nogara, Rogério de Aquino Saraiva, Diones Caeran Bueno, Lílian Juliana Lissner, Cristiane Lenz Dalla Corte, Marcos M. Braga, Denis Broock Rosemberg, João Batista Teixeira Rocha
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/870389

Internet

http://dx.doi.org/10.1155/2015/870389

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