The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons.

We used optical tweezers, video imaging, immunocytochemistry and a variety of inhibitors to analyze the role of Rac1 in the motility and force generation of lamellipodia and filopodia from developing growth cones of isolated Dorsal Root Ganglia neurons. When the activity of Rac1 was inhibited by the...

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Bibliographic Details
Main Authors: Wasim A Sayyad, Paolo Fabris, Vincent Torre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4713067?pdf=render