Heat shock pretreatment improves mesenchymal stem cell viability by heat shock proteins and autophagy to prevent cisplatin-induced granulosa cell apoptosis

Heat shock pretreatment improves mesenchymal stem cell viability by heat shock proteins and autophagy to prevent cisplatin-induced granulosa cell apoptosis

Abstract Background Bone marrow mesenchymal stem cells (BMSCs) can partially repair chemotherapy-induced ovarian damage. However, low survival rate after transplantation hampers the therapeutic efficiency of BMSCs. Heat shock pretreatment (HSP) effectively improves the cell survival. This study atte...

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Bibliographic Details
Main Authors: Qing Wang, Xinran Li, Qingru Wang, Jiaxin Xie, Chuhai Xie, Xiafei Fu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Stem Cell Research & Therapy
Subjects:
Heat shock
Bone marrow mesenchymal stem cells
Apoptosis
Granulosa cells
Cisplatin
Online Access:http://link.springer.com/article/10.1186/s13287-019-1425-4

Internet

http://link.springer.com/article/10.1186/s13287-019-1425-4

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