Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan

Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan

Objective: The Kii Peninsula of Japan is known to be a high incidence area of amyotrophic lateral sclerosis/parkinsonism-dementia complex (Kii ALS/PDC) with tauopathy. Nitrative stress and oxidative stress on ALS/PDC and their relationship to tau pathology were clarified.Methods: Seven patients with...

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Bibliographic Details
Main Authors: Yukiko Hata, Ning Ma, Misao Yoneda, Satoru Morimoto, Hideyuki Okano, Shigeo Murayama, Shosuke Kawanishi, Shigeki Kuzuhara, Yasumasa Kokubo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
parkinsonism-dementia complex
Kii Peninsula
tau
nitrative stress
oxidative stress
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00751/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00751/full

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