Arf6-Dependent Intracellular Trafficking of Pasteurella multocida Toxin and pH-Dependent Translocation from Late Endosomes

The potent mitogenic toxin from Pasteurella multocida (PMT) is the major virulence factor associated with a number of epizootic and zoonotic diseases caused by infection with this respiratory pathogen. PMT is a glutamine-specific protein deamidase that acts on its intracellular G-protein targets to...

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Bibliographic Details
Main Authors: Tracy P. M. Chong, Yuka Bannai, Brenda A. Wilson, Tana L. Repella, Mengfei Ho
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/3/3/218/