Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor

The α4β2 nAChR is implicated in a range of diseases and disorders including nicotine addiction, epilepsy and Parkinson’s and Alzheimer’s diseases. Designing α4β2 nAChR selective inhibitors could help define the role of the α4β2 nAChR in such disease states. In this study, we aimed to modify globular...

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Bibliographic Details
Main Authors: Xiaosa Wu, David J. Craik, Quentin Kaas
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/9/482