TLQP-21 protects human umbilical vein endothelial cells against high-glucose-induced apoptosis by increasing G6PD expression.

Hyperglycemia causes oxidative stress that could damage vascular endothelial cells, leading to cardiovascular complications. The Vgf gene was identified as a nerve growth factor-responsive gene, and its protein product, VGF, is characterized by the presence of partially cleaved products. One of the...

Full description

Bibliographic Details
Main Authors: Wei Zhang, Chao Ni, Jie Sheng, Yanyin Hua, Jiangbo Ma, Lijun Wang, Yu Zhao, Yubo Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836798?pdf=render