Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis
Summary: There are significant ambiguities regarding how DNA polymerase η is recruited to DNA lesion sites in stressed cells while avoiding normal replication forks in non-stressed cells. Even less is known about the mechanisms responsible for Pol η-induced mutations in cancer genomes. We show that...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900421830097X |