The Multifaceted Roles of Copper in Cancer: A Trace Metal Element with Dysregulated Metabolism, but also a Target or a Bullet for Therapy

In the human body, copper (Cu) is a major and essential player in a large number of cellular mechanisms and signaling pathways. The involvement of Cu in oxidation–reduction reactions requires close regulation of copper metabolism in order to avoid toxic effects. In many types of cancer, variations i...

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Bibliographic Details
Main Authors: Pierre Lelièvre, Lucie Sancey, Jean-Luc Coll, Aurélien Deniaud, Benoit Busser
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/12/3594