Optimization of the Light-On system in a lentiviral platform to a light-controlled expression of genes in neurons

Optimization of the Light-On system in a lentiviral platform to a light-controlled expression of genes in neurons

Background: Molecular brain therapies require the development of molecular switches to control gene expression in a limited and regulated manner in time and space. Light-switchable gene systems allow precise control of gene expression with an enhanced spatio-temporal resolution compared to chemical...

Full description

Bibliographic Details
Main Authors: Rafaella V. Zárate, Duxan Arancibia, Anllely Fernández, Janetti R. Signorelli, Luis F. Larrondo, María Estela Andrés, Pedro Zamorano
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Electronic Journal of Biotechnology
Subjects:
GAVPO
Gene expression in neurons
Gene-regulated expression
Lentiviral platform
Lentivirus
Light-controlled expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345821000142

Internet

http://www.sciencedirect.com/science/article/pii/S0717345821000142

Similar Items