Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1

Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1

Cholesterol is an essential lipid in eukaryotic cells and is present in membranes of all intracellular compartments. A major source for cellular cholesterol is internalized lipoprotein particles that are transported toward acidic late endosomes (LE) and lysosomes. Here the lipoprotein particles are...

Full description

Bibliographic Details
Main Authors: Rik van der Kant, Ilse Zondervan, Lennert Janssen, Jacques Neefjes
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Journal of Lipid Research
Subjects:
lysosome
metastatic lymph node 64
oxysterol-binding protein-related protein 1L
ATP binding cassette transporter A3
Niemann Pick disease type C1
STARD3
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520375313

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520375313

Similar Items