Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion

Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion

Abstract Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety of active compounds into the skin. To serve as a substitute for common hypodermic needles, MNs must pierce the human stratum corneum (~ 10 to 20 µm), without rupturing or bending during penetration. T...

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Bibliographic Details
Main Authors: Pooyan Makvandi, Melissa Kirkby, Aaron R. J. Hutton, Majid Shabani, Cynthia K. Y. Yiu, Zahra Baghbantaraghdari, Rezvan Jamaledin, Marco Carlotti, Barbara Mazzolai, Virgilio Mattoli, Ryan F. Donnelly
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:Nano-Micro Letters
Subjects:
Insertion responsive
Implantable microneedles
Skin indentation
Transdermal microneedles
Pain management
Online Access:https://doi.org/10.1007/s40820-021-00611-9

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