Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia

Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia

Repurposing existing drugs represents a promising approach for successful development of acute stroke therapies. In this context, the macrolide antibiotic azithromycin has been shown to exert neuroprotection in mice due to its immunomodulatory properties. Here, we have demonstrated that acute admini...

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Bibliographic Details
Main Authors: Diana Amantea, Francesco Petrelli, Rosaria Greco, Cristina Tassorelli, Maria Tiziana Corasaniti, Paolo Tonin, Giacinto Bagetta
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
azithromycin
drug repurposing
ischemic stroke
neuroprotection
STAT3
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01256/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01256/full

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