The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis
People living with HIV can experience accelerated aging and the development of neurological disorders. Recently, we reported that HIV-1 infection results in a dramatic loss of peroxisomes in macrophages and brain tissue. This is significant because (i) peroxisomes are important for the innate immune...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-03-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.03395-19 |