Alteration of L-Dopa decarboxylase expression in SARS-CoV-2 infection and its association with the interferon-inducible ACE2 isoform.

L-Dopa decarboxylase (DDC) is the most significantly co-expressed gene with ACE2, which encodes for the SARS-CoV-2 receptor angiotensin-converting enzyme 2 and the interferon-inducible truncated isoform dACE2. Our group previously showed the importance of DDC in viral infections. We hereby aimed to...

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Bibliographic Details
Main Authors: George Mpekoulis, Efseveia Frakolaki, Styliani Taka, Anastasios Ioannidis, Alice G Vassiliou, Katerina I Kalliampakou, Kostas Patas, Ioannis Karakasiliotis, Vassilis Aidinis, Stylianos Chatzipanagiotou, Emmanouil Angelakis, Dido Vassilacopoulou, Niki Vassilaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253458