Design, Synthesis and Antifungal Activity of Stapled Aurein1.2 Peptides

Aurein1.2 is a 13-residue antimicrobial peptide secreted by the Australian tree frog <i>Litoria aurea</i>. In order to improve its stabilities, the helical contents and corresponding biological activities of Aurein1.2 (a series of stapled analogues) were synthesized, and their potential...

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Bibliographic Details
Main Authors: Mengjun Zheng, Ruina Wang, Si Chen, Yan Zou, Lan Yan, Linjing Zhao, Xiang Li
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antibiotics
Subjects:
AMP
Online Access:https://www.mdpi.com/2079-6382/10/8/956