High-Salt Diet Induces IL-17-Dependent Gut Inflammation and Exacerbates Colitis in Mice

Excess intake of sodium is often associated with high risk for cardiovascular disease. More recently, some studies on the effects of high-salt diets (HSDs) have also demonstrated that they are able to activate Th17 cells and increase severity of autoimmune diseases. The purpose of the present study...

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Main Authors: Sarah Leão Fiorini Aguiar, Mariana Camila Gonçalves Miranda, Mauro Andrade Freitas Guimarães, Helton Costa Santiago, Camila Pereira Queiroz, Pricila da Silva Cunha, Denise Carmona Cara, Giselle Foureaux, Anderson José Ferreira, Valbert Nascimento Cardoso, Patrícia Aparecida Barros, Tatiani Uceli Maioli, Ana Maria Caetano Faria
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01969/full