Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376

Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376

Porcine epidemic diarrhea virus (PEDV), being highly virulent and contagious in piglets, has caused significant damage to the pork industries of many countries worldwide. There are no commercial drugs targeting coronaviruses (CoVs), and few studies on anti-PEDV inhibitors. The coronavirus 3C-like pr...

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Bibliographic Details
Main Authors: Gang Ye, Xiaowei Wang, Xiaohan Tong, Yuejun Shi, Zhen F. Fu, Guiqing Peng
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Viruses
Subjects:
coronavirus
pedv 3cl<sup>pro</sup>
inhibitor
crystal structure
complex
Online Access:https://www.mdpi.com/1999-4915/12/2/240

Internet

https://www.mdpi.com/1999-4915/12/2/240

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