Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development.

Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development.

While rare pathogenic copy-number variants (CNVs) are associated with both neuronal and non-neuronal phenotypes, functional studies evaluating these regions have focused on the molecular basis of neuronal defects. We report a systematic functional analysis of non-neuronal defects for homologs of 59...

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Bibliographic Details
Main Authors: Tanzeen Yusuff, Matthew Jensen, Sneha Yennawar, Lucilla Pizzo, Siddharth Karthikeyan, Dagny J Gould, Avik Sarker, Erika Gedvilaite, Yurika Matsui, Janani Iyer, Zhi-Chun Lai, Santhosh Girirajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008792

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https://doi.org/10.1371/journal.pgen.1008792

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