HIF-1alpha expression profile in intratumoral and peritumoral inflammatory cells as a prognostic marker for squamous cell carcinoma of the oral cavity.

HIF-1alpha expression profile in intratumoral and peritumoral inflammatory cells as a prognostic marker for squamous cell carcinoma of the oral cavity.

The HIF-1 transcriptional complex is responsible for controlling transcription of over 100 genes involved in cell hypoxia response. HIF-1alpha subunit is stabilized in hypoxia conditions, creating the HIF-1 nuclear transcription factor. In inflammatory cells, high HIF-1alpha expression induces lymph...

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Bibliographic Details
Main Authors: Suzanny Oliveira Mendes, Marcelo dos Santos, Gabriela Tonini Peterle, Lucas de Lima Maia, Elaine Stur, Lidiane Pignaton Agostini, Marcos Brasilino de Carvalho, Eloiza Helena Tajara, Iúri Drumond Louro, Leonardo Oliveira Trivilin, Adriana Madeira Álvares da Silva-Conforti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887011?pdf=render

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http://europepmc.org/articles/PMC3887011?pdf=render

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