Tissue of Origin, but Not XCI State, Influences Germ Cell Differentiation from Human Pluripotent Stem Cells

Tissue of Origin, but Not XCI State, Influences Germ Cell Differentiation from Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) are not only a promising tool to investigate differentiation to many cell types, including the germline, but are also a potential source of cells to use for regenerative medicine purposes in the future. However, current in vitro models to generate human primordia...

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Bibliographic Details
Main Authors: Yolanda W. Chang, Arend W. Overeem, Celine M. Roelse, Xueying Fan, Christian Freund, Susana M. Chuva de Sousa Lopes
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
X chromosome inactivation
pluripotent stem cells
primordial germ cells
differentiation
embryoid bodies
human
Online Access:https://www.mdpi.com/2073-4409/10/9/2400

Internet

https://www.mdpi.com/2073-4409/10/9/2400

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