An In Vitro Method to Manipulate the Direction and Functional Strength Between Neural Populations

An In Vitro Method to Manipulate the Direction and Functional Strength Between Neural Populations

We report the design and application of a MEMs device that permits investigators to create arbitrary network topologies. With this device investigators can manipulate the degree of functional connectivity among distinct neural populations by systematically altering their geometric connectivity in vi...

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Bibliographic Details
Main Authors: Liangbin ePan, Sankaraleengam eAlagapan, Eric eFranca, Stathis eLeondopulos, Thomas B DeMarse, Gregory J Brewer, Bruce C Wheeler
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Neural Circuits
Subjects:
Cortical Synchronization
Cortex
functional connectivity
multielectrode array
dissociated neuronal culture
MEMS (Micro Electro Mechanical Systems)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2015.00032/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2015.00032/full

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