Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

Different subsets and/or polarized phenotypes of monocytes and macrophages may play distinct roles during the development and resolution of inflammation. Here, we demonstrate in a murine model of rheumatoid arthritis that nonclassical Ly6C− monocytes are required for the initiation and progression o...

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Bibliographic Details
Main Authors: Alexander V. Misharin, Carla M. Cuda, Rana Saber, Jason D. Turner, Angelica K. Gierut, G. Kenneth Haines III, Sergejs Berdnikovs, Andrew Filer, Andrew R. Clark, Christopher D. Buckley, Gökhan M. Mutlu, G.R. Scott Budinger, Harris Perlman
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714008158