Single Amino Acid Polymorphisms of Pertussis Toxin Subunit S2 (PtxB) Affect Protein Function.

Whooping cough due to Bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations. Polymorphisms in the pertussis toxin, ptxA and ptxB genes, and the pertactin, prn genes of clinical isolates of Bordetell...

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Bibliographic Details
Main Authors: Scott H Millen, Mineo Watanabe, Eiji Komatsu, Fuminori Yamaguchi, Yuki Nagasawa, Eri Suzuki, Haleigh Monaco, Alison A Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4573519?pdf=render