Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

<p>Abstract</p> <p>Background</p> <p>Immune dysfunction, including monocytosis and increased blood levels of interleukin-1, interleukin-6 and tumour necrosis factor α has been observed during acute episodes of major depression. These peripheral immune processes may be a...

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Main Authors: Mawrin Christian, Sarnyai Zoltán, Bernstein Hans-Gert, Guillemin Gilles J, Gos Tomasz, Walter Martin, Steiner Johann, Brisch Ralf, Bielau Hendrik, zu Schwabedissen Louise, Bogerts Bernhard, Myint Aye-Mu
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/94