Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease

Nanoparticles are being explored as a potential method to target Aβ aggregation in Alzheimer’s disease. Here, the authors develop gold nanoparticles that were capped with chiral L or D-glutathione which has been shown to improve BBB permeability and demonstrate their ability to improve cognitive fun...

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Bibliographic Details
Main Authors: Ke Hou, Jing Zhao, Hui Wang, Bin Li, Kexin Li, Xinghua Shi, Kaiwei Wan, Jing Ai, Jiawei Lv, Dawei Wang, Qunxing Huang, Huayi Wang, Qin Cao, Shaoqin Liu, Zhiyong Tang
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18525-2