GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Abstract Background In spite of the recent discovery of genetic mutations in most myelodysplasic (MDS) patients, the pathophysiology of these disorders still remains poorly understood, and only few in vivo models are available to help unravel the disease. Methods We performed global specific gene ex...

Full description

Bibliographic Details
Main Authors: Laura Guerenne, Stéphanie Beurlet, Mohamed Said, Petra Gorombei, Carole Le Pogam, Fabien Guidez, Pierre de la Grange, Nader Omidvar, Valérie Vanneaux, Ken Mills, Ghulam J Mufti, Laure Sarda-Mantel, Maria Elena Noguera, Marika Pla, Pierre Fenaux, Rose Ann Padua, Christine Chomienne, Patricia Krief
Format: Article
Language:English
Published: BMC 2016-01-01
Series:Journal of Hematology & Oncology
Subjects:
Myelodysplastic syndrome
Mice models
Gene expression profile
MDS
Online Access:http://link.springer.com/article/10.1186/s13045-016-0235-8

Internet

http://link.springer.com/article/10.1186/s13045-016-0235-8

Similar Items