DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

Aberrant expression of immune checkpoints (ICs) in cancer creates an immunosuppressive microenvironment, which supports immune evasion of tumor cells. We have recently reported that epigenetic modifications are critical for ICs expression in the tumor microenvironment (TME) of primary breast cancer...

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Bibliographic Details
Main Authors: Asma A. Elashi, Varun Sasidharan Nair, Rowaida Z. Taha, Hibah Shaath, Eyad Elkord
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
breast cancer
colorectal cancer
immune checkpoints
dna methylation
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1542918

Internet

http://dx.doi.org/10.1080/2162402X.2018.1542918

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