Assessment of Cerebral and Cerebellar White Matter Microstructure in Spinocerebellar Ataxias 1, 2, 3, and 6 Using Diffusion MRI

Development of imaging biomarkers for rare neurodegenerative diseases such as spinocerebellar ataxia (SCA) is important to non-invasively track progression of disease pathology and monitor response to interventions. Diffusion MRI (dMRI) has been shown to identify cross-sectional degeneration of whit...

Full description

Bibliographic Details
Main Authors: Young Woo Park, James M. Joers, Bin Guo, Diane Hutter, Khalaf Bushara, Isaac M. Adanyeguh, Lynn E. Eberly, Gülin Öz, Christophe Lenglet
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00411/full