From trash to treasure: detecting unexpected contamination in unmapped NGS data

From trash to treasure: detecting unexpected contamination in unmapped NGS data

Abstract Background Next Generation Sequencing (NGS) experiments produce millions of short sequences that, mapped to a reference genome, provide biological insights at genomic, transcriptomic and epigenomic level. Typically the amount of reads that correctly maps to the reference genome ranges betwe...

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Bibliographic Details
Main Authors: Mara Sangiovanni, Ilaria Granata, Amarinder Singh Thind, Mario Rosario Guarracino
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Bioinformatics
Subjects:
Contamination
Next generation sequencing
Unmapped reads
Online Access:http://link.springer.com/article/10.1186/s12859-019-2684-x

Internet

http://link.springer.com/article/10.1186/s12859-019-2684-x

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