Gene Variant of the Bradykinin B2 Receptor Influences Pulmonary Arterial Pressures in Heart Failure Patients

Background Pulmonary arterial pressure (PAP) varies considerably in heart failure (HF) despite similar degrees of left ventricular (LV) dysfunction. Bradykinin alters vascular tone and common variations in the kinin B2 receptor (BDKRB2) gene exists. We hypothesized that genetic variation in this rec...

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Bibliographic Details
Main Authors: Thomas P. Olson, Robert P. Frantz, Stephen T. Turner, Kent R. Bailey, Christina M. Wood, Bruce D. Johnson
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
Online Access:https://doi.org/10.4137/CCRPM.S2147