ARQ-197 enhances the antitumor effect of sorafenib in hepatocellular carcinoma cells via decelerating its intracellular clearance

ARQ-197 enhances the antitumor effect of sorafenib in hepatocellular carcinoma cells via decelerating its intracellular clearance

Xudong Gao,1,2 Hebing Chen,1 Xin Huang,1 Hao Li,1 Zhen Liu,1 Xiaochen Bo1 1Beijing Institute of Radiation Medicine, Beijing 100850, People’s Republic of China; 2The 5th Medical Center of PLA General Hospital, Beijing 100039, People’s Republic of China Background: Hepatocellular...

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Bibliographic Details
Main Authors: Gao X, Chen H, Huang X, Li H, Liu Z, Bo X
Format: Article
Language:English
Published: Dove Medical Press 2019-02-01
Series:OncoTargets and Therapy
Subjects:
advanced hepatocellular carcinoma
molecular targeted agents
ARQ-197 and sorafenib
drug clearance
epithelial-mesenchymal transition
multi-drug resistance
Online Access:https://www.dovepress.com/arq-197-enhances-the-antitumor-effect-of-sorafenib-in-hepatocellular-c-peer-reviewed-article-OTT

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https://www.dovepress.com/arq-197-enhances-the-antitumor-effect-of-sorafenib-in-hepatocellular-c-peer-reviewed-article-OTT

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