Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells.

Osteosarcoma is the most common primary malignancy of bone. Even after the traditional standard surgical therapy, metastasis still occurs in a high percentage of patients. Glucose is an important source of metabolic energy for tumor proliferation and survival. Tumors usually overexpress glucose tran...

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Bibliographic Details
Main Authors: I-Shan Hsieh, Rong-Sen Yang, Wen-Mei Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4195676?pdf=render