Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming.

Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming.

Chemoprevention is a pragmatic approach to reduce the risk of colorectal cancer, one of the leading causes of cancer-related death in western countries. In this regard, maslinic acid (MA), a pentacyclic triterpene extracted from wax-like coatings of olives, is known to inhibit proliferation and indu...

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Main Authors: Susana Sánchez-Tena, Fernando J Reyes-Zurita, Santiago Díaz-Moralli, Maria Pilar Vinardell, Michelle Reed, Francisco García-García, Joaquín Dopazo, José A Lupiáñez, Ulrich Günther, Marta Cascante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23527181/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23527181/?tool=EBI

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