Cdx2 Regulates Intestinal EphrinB1 through the Notch Pathway
The majority of colorectal cancers harbor loss-of-function mutations in <i>APC</i>, a negative regulator of canonical Wnt signaling, leading to intestinal polyps that are predisposed to malignant progression. Comparable murine <i>APC</i> alleles also evoke intestinal polyps,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-01-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/12/2/188 |