Long Non-Coding RNA PCAT6 Induces M2 Polarization of Macrophages in Cholangiocarcinoma via Modulating miR-326 and RhoA-ROCK Signaling Pathway

Long Non-Coding RNA PCAT6 Induces M2 Polarization of Macrophages in Cholangiocarcinoma via Modulating miR-326 and RhoA-ROCK Signaling Pathway

LncRNAs can act crucial roles in multiple tumors including cholangiocarcinoma (CCA). M2 polarization of macrophages is crucial for their biological roles in immunologic tolerance, which is able to induce tumorigenesis. Given that increasing evidence have suggested that lncRNAs could participate in m...

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Bibliographic Details
Main Authors: Jianfei Tu, Fazong Wu, Li Chen, Liyun Zheng, Yang Yang, Xihui Ying, Jingjing Song, Chunmiao Chen, Xianghua Hu, Zhongwei Zhao, Jiansong Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
cholangiocarcinoma
PCAT6
miR-326
RhoA
macrophages
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.605877/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.605877/full

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