The role of the orbitofrontal cortex and the nucleus accumbens for craving in alcohol use disorder

Abstract This study aimed to investigate structural and functional alterations of the reward system and the neurobiology of craving in alcohol use disorder (AUD). We hypothesized reduced volume of the nucleus accumbens (NAcc), reduced structural connectivity of the segment of the supero-lateral medi...

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Bibliographic Details
Main Authors: Tobias Bracht, Leila Soravia, Franz Moggi, Maria Stein, Matthias Grieder, Andrea Federspiel, Raphaela Tschümperlin, Hallie M. Batschelet, Roland Wiest, Niklaus Denier
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01384-w