Bicarbonate buffered peritoneal dialysis fluid upregulates angiopoietin-1 and promotes vessel maturation.

Ultrafiltration decline is a progressive issue for patients on chronic peritoneal dialysis (PD) and can be caused by peritoneal angiogenesis induced by PD fluids. A recent pediatric trial suggests better preservation of ultrafiltration with bicarbonate versus lactate buffered fluid; underlying molec...

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Bibliographic Details
Main Authors: Gwendolyn Eich, Maria Bartosova, Christian Tischer, Tanja Tamara Wlodkowski, Betti Schaefer, Sebastian Pichl, Nicole Kraewer, Bruno Ranchin, Karel Vondrak, Max Christoph Liebau, Thilo Hackert, Claus Peter Schmitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5734783?pdf=render