Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia

Large-scale mGluR5 network abnormalities linked to epilepsy duration in focal cortical dysplasia

To determine the extent of metabotropic glutamate receptor type 5 (mGluR5) network abnormalities associated with focal cortical dysplasia (FCD), we performed graph theoretical analysis of [11C]ABP688 PET binding potentials (BPND), which allows for quantification of mGluR5 availability. Undirected gr...

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Bibliographic Details
Main Authors: Jonathan M. DuBois, Sulantha Mathotaarachchi, Olivier G. Rousset, Viviane Sziklas, Jorge Sepulcre, Marie-Christine Guiot, Jeffery A. Hall, Gassan Massarweh, Jean-Paul Soucy, Pedro Rosa-Neto, Eliane Kobayashi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
mGluR5
FCD
Epilepsy
PET
Network
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303892

Internet

http://www.sciencedirect.com/science/article/pii/S2213158220303892

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