The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output.
To develop more detailed models of EBV persistence we have studied the dynamics of virus shedding in healthy carriers. We demonstrate that EBV shedding into saliva is continuous and rapid such that the virus level is replaced in < or =2 minutes, the average time that a normal individual swallows....
Main Authors: | Vey Hadinoto, Michael Shapiro, Chia Chi Sun, David A Thorley-Lawson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2698984?pdf=render |
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