The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output.

To develop more detailed models of EBV persistence we have studied the dynamics of virus shedding in healthy carriers. We demonstrate that EBV shedding into saliva is continuous and rapid such that the virus level is replaced in < or =2 minutes, the average time that a normal individual swallows....

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Bibliographic Details
Main Authors: Vey Hadinoto, Michael Shapiro, Chia Chi Sun, David A Thorley-Lawson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2698984?pdf=render