The JNK-Like MAPK KGB-1 of Caenorhabditis Elegans Promotes Reproduction, Lifespan, and Gene Expressions for Protein Biosynthesis and Germline Homeostasis but Interferes with Hyperosmotic Stress Tolerance

The JNK-Like MAPK KGB-1 of Caenorhabditis Elegans Promotes Reproduction, Lifespan, and Gene Expressions for Protein Biosynthesis and Germline Homeostasis but Interferes with Hyperosmotic Stress Tolerance

Aims: This study focused on the role of the JNK-like MAPK (mitogen-activated protein kinase) KGB-1 (kinase, GLH-binding 1) for osmoprotection and other vital functions. Methods: We mapped KGB-1 expression patterns and determined lifespan, reproduction and survival rates as well as changes in body vo...

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Bibliographic Details
Main Authors: Peter Gerke, Alex Keshet, Ansgar Mertenskötter, Rüdiger J. Paul
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Activator protein 1
Chaperone
FOS
Insulin/IGF receptor ortholog
JUN
Regulatory volume increase
Sperm
Target of rapamycin (TOR)
Online Access:http://www.karger.com/Article/FullText/366392

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http://www.karger.com/Article/FullText/366392

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