Using ex vivo culture to assess dynamic phenotype changes in human prostate macrophages following exposure to therapeutic drugs

Abstract Within the prostate tumor microenvironment (TME) there are complex multi-faceted and dynamic communication occurring between cancer cells and immune cells. Macrophages are key cells which infiltrate and surround tumor cells and are recognized to significantly contribute to tumor resistance...

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Bibliographic Details
Main Authors: Clovis Boibessot, France-Hélène Joncas, Aerin Park, Zohra Berrehail, Jean-François Pelletier, Typhaine Gris, Alain Bergeron, Paul Toren
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98903-y