Potential Disease-Modifying Effects of Lithium Carbonate in Niemann-Pick Disease, Type C1

Potential Disease-Modifying Effects of Lithium Carbonate in Niemann-Pick Disease, Type C1

Background: Niemann-Pick disease type C1 (NP-C1) is a rare, autosomal-recessive neurodegenerative disorder with no United States Food and Drug Administration (FDA)-approved drug. Lithium has been shown to have considerable neuroprotective effects for neurological disorders such as bipolar disorder,...

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Bibliographic Details
Main Authors: Shiqian Han, Huiwen Zhang, Mengni Yi, Xiaoqing Liu, Gustavo H. B. Maegawa, Yunding Zou, Qijun Wang, Dianqing Wu, Zhijia Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
niemann-pick disease
lithium
clinical trial
7-ketocholesterol
NNSS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.667361/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.667361/full

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