RNA Secondary Structure Modulates FMRP’s Bi-Functional Role in the MicroRNA Pathway

RNA Secondary Structure Modulates FMRP’s Bi-Functional Role in the MicroRNA Pathway

MicroRNAs act by post-transcriptionally regulating the gene expression of 30%–60% of mammalian genomes. MicroRNAs are key regulators in all cellular processes, though the mechanism by which the cell activates or represses microRNA-mediated translational regulation is poorly understood. In this revie...

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Bibliographic Details
Main Authors: Phillip Kenny, Stephanie Ceman
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
FMRP
G-Quadruplex
microRNA
MOV10
RNA binding proteins
secondary structure
Online Access:http://www.mdpi.com/1422-0067/17/6/985

Internet

http://www.mdpi.com/1422-0067/17/6/985

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