Multiscale cytometry and regulation of 3D cell cultures on a chip

3D cell culture is more relevant than the two-dimensional format, but methods for parallel analysis and temporal regulation of the microenvironment are limited. Here the authors develop a droplet microfluidics system to perform long-term culture of 3D spheroids, enabling multiscale cytometry of indi...

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Bibliographic Details
Main Authors: Sébastien Sart, Raphaël F.-X. Tomasi, Gabriel Amselem, Charles N. Baroud
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00475-x