Expressing acetylcholine receptors after innervation suppresses spontaneous vesicle release and causes muscle fatigue

Abstract The formation and function of synapses are tightly orchestrated by the precise timing of expression of specific molecules during development. In this study, we determined how manipulating the timing of expression of postsynaptic acetylcholine receptors (AChRs) impacts presynaptic release by...

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Bibliographic Details
Main Authors: Meghan Mott, Victor M. Luna, Jee-Young Park, Gerald B. Downes, Kimberly Epley, Fumihito Ono
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01900-3