Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system

Hypertension is one of the major predisposing factors for neurodegenerative disease characterized with activated renin-angiotensin system (RAS) in both periphery and brain. Vitamin D (VitD) is recently recognized as a pleiotropic hormone with strong neuroprotective properties. While multiple lines o...

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Bibliographic Details
Main Authors: Changmeng Cui, Pengfei Xu, Gongying Li, Yi Qiao, Wenxiu Han, Chunmei Geng, Dehua Liao, Mengqi Yang, Dan Chen, Pei Jiang
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719306949