The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction

The proximal tubular α7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction

Kidney injury: Nicotine and inflammation Nicotine may protect the kidney against ischemic reperfusion (IR) injury by reducing inflammation. IR injury is the tissue damage caused by a temporary block of blood flow leading to lack of oxygen and nutrient supply, followed by return of blood flow (reperf...

Full description

Bibliographic Details
Main Authors: Hwajin Kim, So Ra Kim, Jihyun Je, Kyuho Jeong, Sooji Kim, Hye Jung Kim, Ki Churl Chang, Sang Won Park
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0061-x

Internet

https://doi.org/10.1038/s12276-018-0061-x

Similar Items